Soledad Sevilla studied Fine Arts in the 1960s at the Universitat de Barcelona and attended the seminar on Automatic Generation of Plastic Forms at the Computing Centre of the Universidad de Madrid. In the early eighties, she won a scholarship to study at Harvard University in Boston, USA. Initially practising so-called rational abstraction, her work was subsequently defined by geometry and light. By the eighties, she began to incorporate spatial installations and interventions in her painting, which used the formal device of the grid as a base upon which woven modules and explorations could unfold, with a certain lyricism and expressiveness evolving in later years. Toward the end of the nineties, the grid disappeared from her painting, yet a certain idea of geometry, walls and space was retained through references to the organic world of plant life. Light is a central element in her installations, which often display an underlying geometry. Sevilla has exhibited in historical sites such as the Vélez Blanco Castle in Almeria and some of the courtyards of the Alhambra, and has also conducted formal research into iconic paintings and authors of art history such as Velázquez and Rubens.

With a long exhibition career, Sevilla has had retrospective exhibitions at the Centro José Guerrero, Granada (2015); Galeria Marlborough, Barcelona (2017); Centro de Arte Tomás y Valiente, Fuenlabrada (2018); and Centro Cultual Bancaja, Valencia (2019). Her work is included in collections such as the Museo Nacional Centro de Arte Reina Sofía and Fundación Juan March, Madrid; Museo de Bellas Artes, Bilbao; Artium, Vitoria-Gasteiz; and MACBA, Barcelona, among many others.